Cheap Flights from Buffalo Niagara (BUF) to Santo Domingo (SDQA)

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Find the cheapest month to fly from Buffalo Niagara to Santo Domingo

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Buffalo Niagara to Santo Domingo flights are currently cheapest in June.

Alternative Buffalo Niagara to Santo Domingo routes

Looking for the cheapest, fastest or easiest route from Buffalo Niagara to Santo Domingo? You could fly into the following airports instead.

Buffalo to Santo Domingo: Flight information

The things to know before you go.
Cheapest flight found$247
Cheapest month to flyJune

Finding cheap flights from Buffalo Niagara to Santo Domingo: Frequently asked questions

There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.
The best price we found for a round-trip flight from Buffalo Niagara to Santo Domingo is $430. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Buffalo Niagara to Santo Domingo. But we found flights with one or more stops from $430.
There are no flights flying from Buffalo Niagara to Santo Domingo, as of June 2025.
The cheapest month to fly from Buffalo Niagara to Santo Domingo is usually June 2025.
If you're flying from Buffalo Niagara Airport, the cheapest airport near Santo Domingo is Santo Domingo Las Americas – which is 14.5 miles away from the center of Santo Domingo. We've found flights to this airport from $430.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Buffalo Niagara Airport to Santo Domingo on Thursday, October 9, 2025.
No airlines currently offer direct flights between Buffalo Niagara Airport and Santo Domingo. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.
In June, the average temperature is usually around 81°F. August is typically the warmest month in Santo Domingo, when it usually averages around 88°F. You can expect the least rain in March. The coldest month is January, with temperatures averaging 71°F. The rainiest month is September.
Currently, Delta offers the cheapest flight tickets to Santo Domingo.

Flying from Buffalo Niagara International Airport (BUF) to Santo Domingo: what you need to know

  • Santo Domingo's timezone is UTC-4, which is the same as Buffalo (the location of Buffalo Niagara International Airport).

  • For a stress-free journey, arrive at the airport two hours ahead of international flights and an hour before domestic departures. That way, you won't have to rush to board your BUF to Santo Domingo flight.

  • Heading off during a peak time like school or public holidays? Expect longer lines at check-in and security. To give yourself peace of mind, arrive up to four hours before international flights and two hours before domestic departures.

  • A stopover is the ideal opportunity to take a break from traveling and perhaps even explore another city. When searching for plane tickets from BUF to Santo Domingo, uncheck the 'Direct flights only' box to see where you can stop along the way. Some popular options include:

    • John F. Kennedy International Airport (JFK)

    • Newark Liberty International Airport (EWR)

    • Fort Lauderdale-Hollywood International Airport (FLL)

  • Traveling from central Buffalo to BUF takes about 1 hour 15 minutes on public transport. If you drive, ride-share or get a cab, you'll cover the 8 miles in 20 minutes or so, depending on traffic.

  • Want a stress-free start to your vacation? Stay near BUF. Whether you have an early flight from Buffalo Niagara International Airport to Santo Domingo or want to avoid feeling rushed, these hotels are a convenient choice:

  • Of all flights leaving Buffalo Niagara International Airport, 75.46% touch down on time at their destination.

  • You'll find BUF at Genesee Street.

How to find the cheapest flights from Buffalo Niagara International Airport (BUF) to Santo Domingo

  • The lowest price we've seen for a one-way Buffalo Niagara International Airport to Santo Domingo flight is $247. The cheapest price for a return flight is $430. Remember fares can change due to availability at the time of booking.

  • Don't wait until the last moment. You're more likely to land cheap flights from BUF to Santo Domingo if you book ahead. Airlines often have some fantastic early bird discounts.

  • Scoring cheap tickets from Buffalo Niagara International Airport to Santo Domingo is easier if you're flexible with your travel dates. Try using the 'Whole month' function to access the best prices across the month and pick up an epic deal.

  • Picking up a cheap flight from BUF to Santo Domingo is easy with Price Alerts. All you need to do is set up one of these automatic notifications and we'll let you know when a deal gets even better.

  • Tailor your flights with filters. Pick your ideal arrival and departure times, total journey duration and airlines. You can also sort the results by 'Fastest,' 'Best' or 'Cheapest' flights from Buffalo Niagara International Airport to Santo Domingo.

Airports in Santo Domingo

Las Americas International Airport (SDQ)

  • Las Americas International Airport (SDQ) to the center of Santo Domingo takes about 30 minutes by car. The center is roughly 20 miles away.

  • Look into staying at a hotel close to SDQ if you're coming in on a late flight from Buffalo Niagara International Airport to Santo Domingo. Select one of these accommodation options and avoid the hassle of a long transfer:

  • Travel at your own pace with a Las Americas International Airport rental car. Pick up a set of wheels from Final Rentals, FlexWays or INFINITY RENT and find adventure across Santo Domingo and beyond.

  • Lock in the best rate by booking your vehicle from Las Americas International Airport about one week before your flight from BUF to Santo Domingo.

Dr. Joaquin Balaguer International Airport (JBQ)

  • Dr. Joaquin Balaguer International Airport (JBQ) is roughly 12 miles from the center of Santo Domingo. After your flight from Buffalo Niagara International Airport to Santo Domingo, it'll take you around 25 minutes to get to the heart of the city in a cab or ride-share.

  • Micro Hotel Condo Suites is a comfortable accommodation option within a short drive of JBQ. Unpack your bags here after your BUF to Santo Domingo flight and then hang the 'Do not disturb' sign to enjoy some uninterrupted rest.

  • Grab a Dr. Joaquin Balaguer International Airport rental car and unlock more experiences with your own set of wheels. FlexWays is just moments from your arrival gate, so you'll be on the road in a flash.

  • Get your ideal vehicle, not just whatever's left, by reserving your ride from JBQ in advance. You can also avoid paying more than you have to, especially when the airport is busy.

Best time to go to Santo Domingo

  • Carefully consider your dates before locking in your flight from Buffalo Niagara International Airport to Santo Domingo. The city comes alive during high season, but hotel rates are typically higher and major attractions can get busy. Visit Santo Domingo in the low season for a more relaxed vibe.

  • Book a Buffalo Niagara International Airport to Santo Domingo plane ticket with a departure in September to experience the city during its warmest month. You can expect temperatures to range from 73ºF to 91ºF.

  • February sees average temperatures of between 66ºF and 84ºF. Search for a cheap ticket from BUF to Santo Domingo around that time if you want to travel in cooler conditions.

More about Santo Domingo

  • When it comes to searching for somewhere to lay your head, you'll find the most popular stays in Santo Domingo right here. Explore these hotels once you've locked in your flight from Buffalo Niagara International Airport to Santo Domingo:

  • Every great vacation has to include a little sightseeing. National Palace, Alcazar de Colon and Basilica Cathedral of Santa Maria la Menor are attractions you won't want to skip in Santo Domingo.

Explore more of Dominican Republic

  • La Romana is just one of the many cities in Dominican Republic waiting to be explored after you've seen Santo Domingo. Around 65 miles away to the east, top sights here include Dye Fore Golf Course of Casa de Campo, Minitas Beach and La Estrella Park.

  • Puerto Plata is another well-known destination in Dominican Republic and is around 100 miles north-west of Santo Domingo. No trip is complete without dropping by Fortaleza San Felipe, Teleferico Puerto Plata Cable Car and Malecon Puerto Plata.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.