Flights from Des Moines to Chicago

Flight information Des Moines to Chicago

Cheapest roundtrip price last month


Non-stop airlines


Flights per week


Average flight time, total distance 283 miles

1h 19min

Most popular airline last month


Chicago O'Hare International, Chicago Midway, Chicago Pal-Waukee, Chicago Dupage County and others

5 airports

When you are out and about and traveling around the country, you might find yourself looking for flights from Des Moines, Iowa to Chicago, Illinois. Skyscanner can help you to find the best possible deals on your flight so you can enjoy your travels without breaking your budget.

Flying Out of Des Moines

When you are planning to take off from Des Moines, Iowa, you will be flying from the only airport in the Des Moines area. That airport is the Des Moines International Airport and it served about 2.5 million passengers in 2016.

Des Moines International Airport is a major airport for the Iowa area and can get quite busy at times. It is a good idea to arrive at the airport  a few hours before your flight is scheduled to take off. There are several parking options to choose from when you are traveling through Des Moines International Airport.

The long-term parking lot has a maximum charge of $14 a day but there are also four different economy parking lot options with maximum daily charges of somewhere between $5 and $10 per day depending on the specific lot. Economy lots one, two, and four all offer a free shuttle service to the terminal as well.

Airlines that Fly Between Des Moines and Chicago

As you start to plan your trip from Des Moines to Chicago, you will want to get a feel for what airlines offer travel options between these two midwestern cities. Some of the airlines flying between Des Moines and Chicago include:

  • Delta
  • United
  • American Airlines
  • Southwest

Arriving in Chicago

In Chicago, there are two major airports that you might find yourself flying into. Those two airports are O’Hare International Airport and Chicago Midway International Airport

Chicago Midway International Airport

Chicago Midway International Airport is the smaller of the two Chicago area airports but still serves a large number of passengers on an annual basis. In fact, in 2016, the airport saw nearly 22.7 million passengers pass through its terminals.

If you are planning to fly into Chicago Midway International Airport, you will have your choice of transportation options leaving the airport the CTA (Chicago Transit Authority) Orange Line runs to and from the airport and into Chicago as do the CTA bus lines. You can also catch a taxi or book a limo or rideshare car service if you would prefer.  There are also 10 rental car companies that operate through Chicago Midway International Airport. To get to the car rental center, you can grab a shuttle at the arrivals curb and head on over.

O’Hare International Airport

O’Hare International Airport is the largest airport in the Chicago area and serves nearly 78 million passengers every year. When it comes to transportation from the airport, you will have your pick of several options. The CTA Blue line runs to and from O’Hare International Airport as does the Metra commuter train system. There are also CTA buses that operate routes through O’Hare. And, of course there are rideshare, taxi, limo, and rental car options as well.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.