Cheap Flights from Santa Ana John Wayne to Chicago in 2019

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Estimated lowest prices only. Found in the last 14 days.

Flight information Santa Ana John Wayne to Chicago

Cheapest roundtrip price last month


Non-stop airlines


Flights per week


Average flight time, total distance 1709 miles

3h 58min

Most popular airline last month

American Airlines

Chicago O'Hare International, Chicago Midway, Chicago Pal-Waukee, Chicago Dupage County and others

5 airports

Flying Out of Santa Ana John Wayne Airport

John Wayne Airport is located in the heart of Orange County, and it is convenient to downtown Los Angeles, Hollywood and area attractions like Disney. John Wayne Airport is home to a number of major airlines, but its biggest carriers are Southwest Airlines, American Airlines, Delta Airlines, Alaska Airlines and United Airlines.

John Wayne Airport offers a large number of direct flights each day, including to Chicago. Direct flights from John Wayne Airport to Chicago average just over five hours, and they are generally the most convenient option. Even so, travelers with flexibility may be able to save money by booking a connecting flight instead.

Flights with connections are plentiful from John Wayne Airport, and they are often less expensive than direct flights to the same destinations. Travelers may also be able to save money by choosing an alternative airport, and there are several options in the Orange County/Los Angeles area.

The area is also home to the enormous Los Angeles International Airport, or LAX for short, as well as the much smaller Van Nuys Airport. Travelers to American cities and international destinations can often find cheap flights from these alternative airports, so it is important to shop around.

Chicago Airport Options

The city of Chicago is home to a number of major airports, including O’Hare and Midway. O’Hare is the largest Chicago area airport, and it is served by all major U.S. carriers and a number of international airlines as well. Midway is smaller, but it is served by discount airlines like Southwest. That can make Midway a better choice for budget-minded travelers, although airfare prices at O’Hare are often competitive as well.

Tips for Travelers to Chicago

The city of Chicago is a major tourist destination for both domestic and international travelers, and the home to many world-class attractions. Shoppers should be sure to check out the Miracle Mile, an expanse of high-end shops and luxury retailers. The city is also home to other major shopping venues, from large enclosed malls to outdoor plazas.

Nature lovers should be sure to visit the Shedd Aquarium, with its wide assortment of sea creatures and many educational exhibits. The Navy Pier is another must-see attraction, and it is a favorite spot for people watching as well. The Art Institute is one of the best museums in the world, with works from the most famous artists in the world and a rotating series of exhibits.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.