Cheap Flights from St Louis (STL) to Des Moines (DSM)

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      Compare St Louis to Des Moines flight deals

      Find the cheapest month or even day of the year to fly to Des Moines

      Book the best Des Moines fare with no extra fees

      Flight deals from St Louis to Des Moines

      Looking for a cheap last-minute deal or the best round-trip flight from St Louis to Des Moines? Find the lowest prices on one-way and round-trip tickets right here.

      Find the cheapest month to fly from St Louis to Des Moines

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like St Louis to Des Moines flights are currently cheapest in August.

      Direct flights from St Louis to Des Moines

      St Louis to Des Moines: Alternative routes

      Compare routes from St Louis to Des Moines below. You may find an airport to fly into that's cheaper, faster, or easier than Des Moines.

      St Louis to Des Moines: Flight information

      The things to know before you go.
      Cheapest flight found$39
      Cheapest month to flyAugust
      Average flight time1 hr, 10 mins
      Most popular airlineSouthwest Airlines
      Average flights per week15

      Finding cheap flights from St Louis to Des Moines: Frequently asked questions

      The best price we found for a round-trip flight from St Louis to Des Moines is $77. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      1 hour and 10 minutes is the average flight time from St Louis to Des Moines.
      Southwest Airlines flies direct from St Louis to Des Moines.
      There are 15 flights per week flying from St Louis to Des Moines, as of July 2025.
      The cheapest month to fly from St Louis to Des Moines is usually August.
      After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from St Louis Airport to Des Moines Airport on Wednesday, August 13, 2025.
      Yes – the average flight time is 1 hour and 10 minutes.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Des Moines but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
      We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Des Moines is around 40 days in advance, so don’t leave your flight to the last minute.
      Currently, Southwest Airlines offers the cheapest flight tickets to Des Moines.

      Traveling from Lambert-St. Louis International Airport (STL) to Des Moines International Airport (DSM): what you need to know

      • The average duration of a direct flight from Lambert-St. Louis International Airport to Des Moines International Airport is 1 hour 10 minutes.

      • Every week, there are ten Lambert-St. Louis International Airport to Des Moines International Airport flights. If you prefer to take off early, pick the 09:40 Southwest Airlines flight. If you'd rather make the most of your day before flying, the last departure is at 22:55 with Southwest Airlines.

      • Give yourself plenty of time to make your STL to DSM flight. As a rule of thumb, arrive two hours before international departures and an hour ahead for domestic flights.

      • During popular months such as July, you'll want to get to the airport even earlier. Arrive two hours before domestic departures and four hours ahead for an international flight when you fly during peak periods in general.

      • Southwest Airlines is your ticket to exploring Des Moines (and maybe even some other exciting parts of United States!). Check out the direct flights from Lambert-St. Louis International Airport to Des Moines International Airport offered by this carrier.

      • The airline with the highest passenger demand on this route is Southwest Airlines.

      • Southwest Airlines is the most punctual carrier that offers STL to DSM flights. An exceptional 81.9% of its departures on this route arrive on time.

      • We make it a breeze to book a flight with a stopover. To see your options for tickets from Lambert-St. Louis International Airport to Des Moines International Airport, uncheck 'Direct flights only.' Then, pick a flight offering a stop long enough to explore your chosen city. Some great stopovers between STL and DSM include:

        • O'Hare International Airport

        • Nashville International Airport

        • Detroit Metropolitan Wayne County Airport

      How to find the cheapest flights from Lambert-St. Louis International Airport (STL) to Des Moines International Airport (DSM)

      • Right now, $39 is the cheapest price we've found for a one-way Lambert-St. Louis International Airport to Des Moines International Airport flight. The best price for a return ticket is $77. Remember that fares may change due to availability at the time of booking.

      • To score cheap tickets from STL to DSM, book your trip seven months before your departure.

      • The cheapest month for flights from Lambert-St. Louis International Airport to Des Moines International Airport is June. Use the 'Whole month' tool to find the lowest prices if you have flexible dates.

      • You won't have to check back in every day to see if fares have gone down when you create a Price Alert. We'll notify you the moment there's a better deal on cheap flights from STL to DSM.

      • Tailor your flights using filters. Select your ideal arrival and departure times, airlines and total journey duration. You can also sort the results by 'Best,' 'Cheapest' or 'Fastest' flights from Lambert-St. Louis International Airport to Des Moines International Airport.

      Handy information about Lambert-St. Louis International Airport (STL)

      Arriving at Des Moines International Airport (DSM)

      Getting from Des Moines International Airport (DSM) to central Des Moines

      • You'll find DSM at 5800 Fleur Drive, Suite 201.

      • From Des Moines International Airport, Des Moines is approximately 6 miles away. It takes around 15 minutes to drive to the center.

      • If you're taking public transport, expect a journey time of roughly 45 minutes.

      When to fly to Des Moines International Airport (DSM)

      • It's time to pick your travel dates for your flight from Lambert-St. Louis International Airport to Des Moines International Airport. July is the most popular month to visit Des Moines. If you'd like a quieter vibe, go in April.

      • When reserving your flight from Lambert-St. Louis International Airport to Des Moines International Airport, think about the kind of weather you like. July is the warmest month in Des Moines, with temperatures ranging from 59ºF to 88ºF.

      • January has average temperatures of between 9ºF and 36ºF. Look for cheap tickets from STL to DSM around that time if you want to travel when it's cooler.

      Explore more of United States

      • You've seen Des Moines, now it's time to explore more of United States. Travel around 310 miles east to Chicago to check off its must-visit sights. From Millennium Park to Art Institute of Chicago and LandShark Beer Garden at Navy Pier, there's plenty to keep you on the go.

      • If you want to check out another side of United States, head for Milwaukee, about 310 miles east of Des Moines. Miller Park, Pabst Mansion and Milwaukee Public Museum are the start of reasons to visit.

      Prices shown on this page are estimated lowest prices only. Found in the last 45 days.