Cheap Flights from Syracuse (SYR) to Des Moines (DSM)

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      Travelers and cabin class, 1 Adult, Economy

      Compare Syracuse to Des Moines flight deals

      Find the cheapest month or even day of the year to fly to Des Moines

      Book the best Des Moines fare with no extra fees

      Find the cheapest month to fly from Syracuse to Des Moines

      We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Syracuse to Des Moines flights are currently cheapest in June.

      Syracuse to Des Moines: Alternative routes

      Compare routes from Syracuse to Des Moines below. You may find an airport to fly into that's cheaper, faster, or easier than Des Moines.

      Syracuse to Des Moines: Flight information

      The things to know before you go.
      Cheapest flight found$98
      Cheapest month to flyJune

      Finding cheap flights from Syracuse to Des Moines: Frequently asked questions

      The best price we found for a round-trip flight from Syracuse to Des Moines is $381. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
      Currently, there are no airlines that fly direct from Syracuse to Des Moines. But we found flights with one or more stops from $381.
      There are no flights flying from Syracuse to Des Moines, as of May 2025.
      The cheapest month to fly from Syracuse to Des Moines is usually May 2025.
      After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Syracuse Airport to Des Moines Airport on Friday, May 23, 2025.
      No airlines currently offer direct flights between Syracuse Airport and Des Moines Airport. Most routes have one or more stops.
      We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Des Moines but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
      We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Des Moines is around 40 days in advance, so don’t leave your flight to the last minute.
      Currently, American Airlines offers the cheapest flight tickets to Des Moines.

      Flying from Hancock International Airport (SYR) to Des Moines International Airport (DSM): what you need to know

      • Arrive at the airport on time so you don't miss your SYR to DSM flight. Be there at least two hours ahead for international flights and an hour early for domestic departures to avoid a last-minute sprint to the gate.

      • During popular months like July, you'll want to get to the airport earlier. Arrive two hours before domestic departures and four hours ahead of international flights whenever you're traveling during peak periods in general.

      • Think about adding a stopover when booking your ticket from Hancock International Airport to Des Moines International Airport. Just uncheck 'Direct flights only' to break up your journey, or maybe even explore a new city along the way. Here are some options between SYR and DSM:

        • Detroit Metropolitan Wayne County Airport

        • O'Hare International Airport

        • Minneapolis-St. Paul International Airport

      How to find the cheapest flights from Hancock International Airport (SYR) to Des Moines International Airport (DSM)

      • $98 is currently the best price for a one-way Hancock International Airport to Des Moines International Airport flight. A return flight starts at $381. These fares may change depending on availability and demand.

      • Don't wait until the last moment. You're more likely to find cheap tickets from SYR to DSM if you book early. Airlines often have some excellent early bird rates.

      • If you can be flexible with your travel dates, use the 'Whole month' tool. It'll show you the cheapest price across each month when looking for your flight from Hancock International Airport to Des Moines International Airport.

      • Getting your hands on cheap flights from SYR to DSM is easy with Price Alerts. Simply create one of these automatic alerts and we'll get in touch as soon as there's a better deal.

      • Tailor your flights with filters. Select your ideal departure and arrival times, total journey duration and airlines. You can also sort results by 'Best,' 'Fastest' or 'Cheapest' flights from Hancock International Airport to Des Moines International Airport.

      Handy information about Hancock International Airport (SYR)

      • You'll find SYR at City Hall.

      • Of all flights leaving Hancock International Airport, 72.76% arrive on time at their destination.

      • Hancock International Airport is about 11 miles from central Syracuse. If you're catching a cab, ride-sharing or driving from the center, it'll take you 25 minutes or so to get there, depending on the traffic.

      • The journey when using public transport usually takes 1 hour 10 minutes.

      • Looking for a convenient hotel near SYR? If you've booked an early flight from Hancock International Airport to Des Moines International Airport, these accommodation options will have you moments from your departure lounge:

      Arriving at Des Moines International Airport (DSM)

      Getting from Des Moines International Airport (DSM) to central Des Moines

      • You'll find DSM at 5800 Fleur Drive, Suite 201.

      • From Des Moines International Airport, Des Moines is approximately 6 miles away. It takes around 15 minutes to reach the center by car.

      • Traveling to the center on public transport typically takes 45 minutes.

      When to fly to Des Moines International Airport (DSM)

      • July is the most popular month for flights from Hancock International Airport to Des Moines International Airport. For a quieter experience, head to Des Moines in April.

      • When reserving your flight from Hancock International Airport to Des Moines International Airport, consider the kind of weather you enjoy. July is the warmest month in Des Moines, with the temperature ranging from 59ºF to 88ºF.

      • January has average temperatures of between 9ºF and 36ºF. Search for cheap tickets from SYR to DSM sometime then if you want to travel in cooler conditions.

      Explore more of United States

      • Chicago is just one of the many places in United States waiting to be explored once you've seen Des Moines. Around 310 miles away to the east, popular attractions include Millennium Park, Art Institute of Chicago and LandShark Beer Garden at Navy Pier.

      • If you're interested in discovering another side of United States, head for Milwaukee, roughly 310 miles east of Des Moines. Miller Park, Pabst Mansion and Milwaukee Public Museum are the start of reasons to visit.

      Prices shown on this page are estimated lowest prices only. Found in the last 45 days.