$175 Flights from Santa Ana John Wayne (SNA) to Medellin (MDEA)

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Flight deals from Santa Ana John Wayne to Medellin

Looking for a cheap last-minute deal or the best round-trip flight from Santa Ana John Wayne to Medellin? Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Santa Ana John Wayne to Medellin

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Santa Ana John Wayne to Medellin flights are currently cheapest in January.

Alternative Santa Ana John Wayne to Medellin routes

Looking for the cheapest, fastest or easiest route from Santa Ana John Wayne to Medellin? You could fly into the following airports instead.

Santa Ana to Medellin: Flight information

The things to know before you go.
Cheapest flight found$175
Cheapest month to flyJanuary

Finding cheap flights from Santa Ana John Wayne to Medellin: Frequently asked questions

There are 2 airports in Medellin: Medellin Enrique Olaya Herrera and José María Córdova International.
The best price we found for a round-trip flight from Santa Ana John Wayne to Medellin is $495. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Santa Ana John Wayne to Medellin. But we found flights with one or more stops from $495.
There are no flights flying from Santa Ana John Wayne to Medellin, as of December 2025.
The cheapest month to fly from Santa Ana John Wayne to Medellin is usually February.
If you're flying from Santa Ana John Wayne Airport, the cheapest airport near Medellin is José María Córdova International – which is 11.8 miles away from the center of Medellin. We've found flights to this airport from $495.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Santa Ana John Wayne Airport to Medellin on Thursday, February 19, 2026.
No airlines currently offer direct flights between Santa Ana John Wayne Airport and Medellin. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Medellin but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Medellin is around 40 days in advance, so don’t leave your flight to the last minute.
In December, the average temperature is usually around 64°F. May is typically the warmest month in Medellin, when it usually averages around 70°F. You can expect the least rain in January. The coldest month is November, with temperatures averaging 58°F. The rainiest month is May.
Currently, Spirit Airlines offers the cheapest flight tickets to Medellin.

Flying from John Wayne Airport (SNA) to Medellin: what you need to know

  • The timezone in Medellin is UTC-5. The city is two hours ahead of Santa Ana, where John Wayne Airport is located.

  • For a smooth journey, arrive at the airport two hours ahead of international flights and one hour before domestic departures. This leaves you with plenty of time to board your SNA to Medellin flight.

  • Longer lines at security and check-in are likely if you're flying during high season, so allow even more breathing space. A good rule of thumb for peak times? Get there up to four hours early for international flights and at least two hours for domestic departures.

  • Stopovers offer the opportunity to visit a new city or just have a break during your travels. When searching for a plane ticket from SNA to Medellin, uncheck 'Direct flights only' to browse all potential stops. John F. Kennedy International Airport (JFK) is one of your options.

  • Traveling from central Santa Ana to SNA takes about 1 hour 5 minutes by public transport. If you ride-share, drive or get a cab, you'll cover the 5 miles in 15 minutes or so, depending on traffic conditions.

  • Want a relaxed start to your trip? Stay near SNA. Whether you're catching an early flight from John Wayne Airport to Medellin or just don't want to be rushed, these hotels are just the thing:

  • John Wayne Airport gets high marks for on-time performance. 81.53% of flights that depart SNA arrive at their destination as scheduled.

  • SNA's address is 18601 Airport Way.

How to find the cheapest flights from John Wayne Airport (SNA) to Medellin

  • $175 is the cheapest price we've found for a one-way John Wayne Airport to Medellin flight. A return ticket right now is $495. Depending on how early you book and the availability, these fares can change.

  • Don't leave things to the last moment. You're more likely to find cheap flights from SNA to Medellin if you book early. Airlines often offer some fantastic early bird discounts.

  • Landing cheap tickets from John Wayne Airport to Medellin is more likely if you can be flexible with your trip dates. Try using the 'Whole month' tool to access the lowest fares across the month and score an awesome deal.

  • Finding a cheap flight from SNA to Medellin couldn't be easier with Price Alerts. Simply set up one of these automatic notifications and we'll notify you when there's a better deal.

  • Choose your preferred arrival and departure times, number of stops and airlines with our filters. Then, sort the results for your flight from John Wayne Airport to Medellin by 'Cheapest,' 'Best' or 'Fastest.'

Airports in Medellin

Jose Maria Cordova International Airport (MDE)

  • Jose Maria Cordova International Airport (MDE) to the center of Medellin takes around 35 minutes to reach by car. The center is roughly 15 miles away.

  • The last thing you need is a lengthy journey to your hotel if you're landing late on a flight from John Wayne Airport to Medellin. Book one of these accommodation options near MDE instead:

  • Pick up a Jose Maria Cordova International Airport rental car and discover Medellin and beyond with your own set of wheels. Localiza, Green Motion and Confort Rent a Car are well-known companies you can book with here.

  • Secure the lowest price by reserving your ride from Jose Maria Cordova International Airport around one week in advance of your flight from SNA to Medellin.

Enrique Olaya Herrera Airport (EOH)

  • Once your flight from John Wayne Airport to Medellin has hit the runway, you can reach the city center in around 15 minutes by car. Central Medellin is roughly 4 miles from Enrique Olaya Herrera Airport (EOH).

  • If you choose to travel on public transport, you'll get to the city center in 30 minutes or so.

  • After stepping off your SNA to Medellin flight, tuck yourself in at a hotel close to EOH. These are some great accommodation options that'll help you get into relaxation mode:

  • Pick up an Enrique Olaya Herrera Airport rental car and make every stop one of your choosing. You can choose from top rental outlets like Confort Rent a Car and Green Motion.

  • Get first dibs on the best options. Securing your ride from EOH one week in advance often means more savings and a wider choice of vehicles.

Best time to go to Medellin

  • Before locking in your flights from John Wayne Airport to Medellin, consider which time of year works best for you. Peak season in Medellin offers a lively atmosphere and plenty of things to do, while the low season brings better hotel deals and smaller crowds.

  • The warmest month in Medellin is August, with temperatures ranging between 52ºF and 81ºF. Lock in your John Wayne Airport to Medellin plane ticket then if that's the weather you find most pleasant.

  • July sees average temperatures of between 52ºF and 81ºF. Search for a cheap ticket from SNA to Medellin around that time if you want to travel when it's cooler.

More about Medellin

  • Start your Medellin trip right by choosing the perfect place to stay. As soon as you've booked your flight from John Wayne Airport to Medellin, browse our selection of hotels including:

  • All great vacations should include a little sightseeing. Botero Plaza, Parque Arvi and Pueblito Paisa are must-visits when exploring Medellin.

Explore more of Colombia

  • You've visited Medellin, now it's time to explore other parts of Colombia. Travel about 150 miles south-east to Bogota to check off its leading attractions. From Gold Museum to Usaquen Train Station and Urbanización Villas del Madrigal - Molino del Viento Park, you've got a jam-packed schedule ahead.

  • Cali is another essential stop in Colombia and is around 200 miles south of Medellin. No journey is complete without dropping by Cristo Rey, Gato de Tejada and Caliwood Museo de la Cinematografia.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.