$439 Flights from Lisbon (LIS) to Santo Domingo (SDQA)

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Flight deals from Lisbon to Santo Domingo

Looking for a cheap last-minute deal or the best round-trip flight from Lisbon Airport to Santo Domingo? If you want to travel next month, round-trip fares start from $840. Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Lisbon to Santo Domingo from $439 one-way

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Lisbon to Santo Domingo flights are currently cheapest in September.

Alternative Lisbon to Santo Domingo routes

Looking for the cheapest, fastest or easiest route from Lisbon to Santo Domingo? You could fly into the following airports instead.

Lisbon to Santo Domingo: Flight information

The things to know before you go.
Cheapest flight found$439
Cheapest month to flySeptember

Finding cheap flights from Lisbon to Santo Domingo: Frequently asked questions

There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.
The best price we found for a round-trip flight from Lisbon to Santo Domingo is $729. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
Currently, there are no airlines that fly direct from Lisbon to Santo Domingo. But we found flights with one or more stops from $729.
There are no flights flying from Lisbon to Santo Domingo, as of May 2026.
The cheapest month to fly from Lisbon to Santo Domingo is usually September.
If you're flying from Lisbon Airport, the cheapest airport near Santo Domingo is Santo Domingo Las Americas – which is 14.5 miles away from the center of Santo Domingo. We've found flights to this airport from $729.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Lisbon Airport to Santo Domingo on Monday, September 7, 2026.
No airlines currently offer direct flights between Lisbon Airport and Santo Domingo. Most routes have one or more stops.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.
In May, the average temperature is usually around 81°F. August is typically the warmest month in Santo Domingo, when it usually averages around 88°F. You can expect the least rain in March. The coldest month is January, with temperatures averaging 71°F. The rainiest month is September.
Currently, Air Europa offers the cheapest flight tickets to Santo Domingo.

Flying from Lisbon Humberto Delgado Airport (LIS) to Santo Domingo: what you need to know

  • The timezone in Santo Domingo is UTC-4. The city is four hours behind Lisbon, where Lisbon Humberto Delgado Airport is located.

  • For hassle-free travel, arrive at the airport two hours ahead of international flights and an hour before domestic departures. This will give you plenty of time to board your LIS to Santo Domingo flight.

  • Flying during a popular month like August? Major public holidays and other popular seasons can lead to longer queues at check-in and security. Play things extra safe and get there up to four hours ahead of international flights and two hours before domestic departures.

  • Consider adding a stopover to potentially find a cheaper plane ticket from LIS to Santo Domingo. Just deselect 'Direct flights only' during your search. Take a detour (and maybe pocket some savings) by stopping at one of these connection hubs:

    • New York John F. Kennedy International Airport (JFK)

    • Newark Liberty International Airport (EWR)

    • Adolfo Suarez Madrid-Barajas Airport (MAD)

  • LIS is about 4 miles from central Lisbon. If you're ride-sharing, driving or catching a cab from the center, it'll take you 20 minutes or so to get there, depending on the traffic. If you're using public transport, expect the travel time to be around 25 minutes.

  • Want an easy start to your vacation? Stay near LIS. Whether you're catching an early flight from Lisbon Humberto Delgado Airport to Santo Domingo or want to avoid feeling rushed, these hotels are all about convenience:

  • Of all flights leaving Lisbon Humberto Delgado Airport, 56% touch down on time at their destination.

How to find the cheapest flights from Lisbon Humberto Delgado Airport (LIS) to Santo Domingo

  • The best price we've seen for a one-way Lisbon Humberto Delgado Airport to Santo Domingo flight is $439. The cheapest price for a return flight is $729. Remember fares can change due to demand at the time of booking.

  • Booking ahead of time is often the key to scoring a cheap flight from LIS to Santo Domingo. Flight prices rise as demand increases, so the closer you get to departure, the more you'll likely spend on your ticket.

  • Landing cheap tickets from Lisbon Humberto Delgado Airport to Santo Domingo is easier if you're flexible with your travel dates. Try using the 'Whole month' search function to access the lowest fares across the month and score a fantastic deal.

  • Never miss a deal on cheap flights from LIS to Santo Domingo by setting up a Price Alert. You'll receive an email or notification through the app when fares go down.

  • Save money on your flight from Lisbon Humberto Delgado Airport to Santo Domingo with the help of our filters. Select your ideal duration, departure time and airlines, then sort the results by 'Cheapest' for the best deals.

Airports in Santo Domingo

Santo Domingo Las Americas International Airport (SDQ)

  • Santo Domingo Las Americas International Airport (SDQ) is around 18 miles from the center of Santo Domingo. If you're getting a cab or a ride-share, the drive takes about 35 minutes.

  • It takes around 1 hour 15 minutes if you're traveling by public transport.

  • If you have a late flight from Lisbon Humberto Delgado Airport to Santo Domingo, few things beat the convenience of staying close to the terminal. Grab your suitcases from the carousel and then be showered and sleeping not long after at one of these accommodation options near SDQ:

  • Booking your ride from Santo Domingo Las Americas International Airport around one week in advance of your flight from LIS to Santo Domingo can help you lock in the best possible rate.

La Isabela Dr Joaquin Balaguer Intl Airport (JBQ)

  • Once your flight from Lisbon Humberto Delgado Airport to Santo Domingo has hit the tarmac, you can reach the city center in about 30 minutes by car. Central Santo Domingo is roughly 14 miles from La Isabela Dr Joaquin Balaguer Intl Airport (JBQ).

  • If you travel by public transport, you'll reach the center in 50 minutes or so.

  • Hang the 'Do not disturb' sign on your door and rest at a hotel near JBQ. Here are a few options where you can kick back after your LIS to Santo Domingo flight:

  • Avoid filling out paperwork at the rental desk by completing your booking beforehand. Secure your ride from JBQ a few weeks in advance so you can simply grab the keys and be on your way.

Best time to go to Santo Domingo

  • It's time to pick your travel dates for your flight from Lisbon Humberto Delgado Airport to Santo Domingo. August is the most popular month for a trip to Santo Domingo. If you want a quieter vibe, go in December.

  • Before booking a Lisbon Humberto Delgado Airport to Santo Domingo plane ticket, think about what kind of weather works for you. September is the warmest month in Santo Domingo, with temperatures ranging from 73ºF to 91ºF.

  • If you want cooler conditions, look for a cheap ticket from LIS to Santo Domingo in February when temperatures average between 66ºF and 84ºF.

More about Santo Domingo

  • Once you've booked your flight from Lisbon Humberto Delgado Airport to Santo Domingo, find a hotel that offers the right mix of comfort and location. Make one of these options your base for exploring Santo Domingo:

  • There are so many things to see and do in this city it can be hard to work out where to start. Alcazar de Colon, Catedral Primada de las Americas and The Cathedral of the Americas are leading attractions which should feature on any good Santo Domingo itinerary.

Explore more of the Dominican Republic

  • Santo Domingo is always a good idea, but there are so many other corners of the Dominican Republic just waiting to be discovered. About 65 miles east of Santo Domingo, a trip to La Romana will fill your itinerary to the brim. Start with attractions like Altos de Chavon, Minitas Beach and Dye Fore Golf Course of Casa de Campo.

  • Puerto Plata is another well-known destination in the Dominican Republic and is around 100 miles northwest of Santo Domingo. No journey is complete without seeing Long Beach, Golden Beach (Playa Dorada) and Puerto Plata Cable Car.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.