$248 Flights from Panama City (PTYA) to Chicago (CHIA)

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Flight deals from Panama City to Chicago

Looking for a cheap last-minute deal or the best round-trip flight from Panama City to Chicago? Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Panama City to Chicago

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Panama City to Chicago flights are currently cheapest in January.

Alternative Panama City to Chicago routes

Looking for the cheapest, fastest or easiest route from Panama City to Chicago? You could fly into the following airports instead.

Panama City to Chicago: Flight information

The things to know before you go.
Cheapest flight found$248
Cheapest month to flyJanuary
Average flight time5 hrs, 44 mins
Most popular airlineCopa
Average flights per week272

Finding cheap flights from Panama City to Chicago: Frequently asked questions

There are 4 airports in Chicago: Chicago Midway, Chicago O'Hare International, Chicago Dupage County, and Chicago Rockford.
The best price we found for a round-trip flight from Panama City to Chicago is $473. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
5 hours and 44 minutes is the average flight time from Panama City to Chicago.
Copa, United and EVA Air fly direct from Panama City to Chicago.
There are 68 flights per week flying from Panama City to Chicago, as of December 2025.
The cheapest month to fly from Panama City to Chicago is usually February.
If you're flying from Panama City, the cheapest airport near Chicago is Chicago O'Hare International – which is 15.8 miles away from the center of Chicago. We've found flights to this airport from $473.
After crunching the numbers on our flight calendar, we found that it is currently cheapest to fly from Panama City to Chicago on Monday, February 9, 2026.
Yes – the average flight time is 5 hours and 44 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Chicago but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Chicago is around 40 days in advance, so don’t leave your flight to the last minute.
In December, the average temperature is usually around 29°F. July is typically the warmest month in Chicago, when it usually averages around 80°F. You can expect the least rain in January. The coldest month is January, with temperatures averaging 18°F. The rainiest month is August.
The cheapest airline that flies to Chicago is Wingo, and the cheapest airline that flies to Chicago O'Hare International Airport is Copa.

Flying from Panama City to Chicago: what you need to know

  • Panama City has two main airports where you can set off on your adventure. Check out your options for booking a flight from Panama City to Chicago leaving from Tocumen International Airport (PTY) or Panama Pacifico Airport (BLB).

  • When it comes to working out where to land in Chicago, O'Hare International Airport (ORD) and Chicago Midway International Airport (MDW) are the chief entry points.

  • The average time for a direct Panama City to Chicago flight is 5 hours 45 minutes.

  • Panama City and Chicago follow the same timezone, UTC-5.

  • Tocumen International Airport (PTY) to O'Hare International Airport (ORD) is the most traveled route between these two cities. There are 11 flights a week to choose from. If you have things to finalize before heading off, the last flight from Panama City to Chicago is with Copa Airlines at 18:45. Opt for the first PTY to ORD departure operated by Copa Airlines at 07:39 to make the most of your arrival in Chicago.

  • For a relaxed travel experience, turn up at the airport two hours ahead of international flights and one hour before domestic departures. This will give you plenty of time to catch your Panama City to Chicago flight.

  • You can expect longer lines in popular months such as June. Arriving up to four hours ahead of international flights and two hours for a domestic departure is a wise move.

How to find the cheapest flights from Panama City to Chicago

  • Book two months before flying. Pricing trends suggest that this is the ideal window for finding cheap Panama City to Chicago flights.

  • May is the best month for picking up an amazing deal on a plane ticket from Panama City to Chicago. If you'd like to travel during a different time of year, the 'Whole month' tool will give you the lowest prices for every month.

  • Locking in a cheap flight from Panama City to Chicago couldn't be easier with Price Alerts. All you need to do is create one of these automatic alerts and we'll let you know as soon as there's a better deal.

  • Find a cheap Panama City to Chicago flight with the help of our filters. Select your preferred departure time, duration and airlines, then sort the results by 'Cheapest' for the best deals.

Flying from Panama City

Tocumen International Airport (PTY)

  • If you're searching for a direct flight from Panama City to Chicago, you can depart from Tocumen International Airport (PTY). Get from PTY to O'Hare International Airport (ORD) in one continuous trip.

  • Reserve your Panama City to Chicago plane tickets with Copa Airlines. This carrier is a top choice for direct flights from PTY.

  • We make it a cinch to book a Panama City to Chicago flight with a stopover. To see all your options departing from Tocumen International Airport, uncheck 'Direct flights only.' Then, select a flight that has a stop long enough to see the sights of the city of your choice. Top stopovers include:

    • Hartsfield-Jackson Atlanta International Airport (ATL)

    • Los Angeles International Airport (LAX)

    • Miami International Airport (MIA)

  • PTY is about 11 miles from central Panama City. If you're driving, ride-sharing or catching a cab from the center, it'll take 20 minutes or so to get there, depending on the traffic. If you're planning to take public transport, expect the trip time to be around 1 hour 5 minutes.

  • Looking for a handy hotel near Tocumen International Airport? If you're catching an early flight from Panama City to Chicago, these accommodation options will have you sleeping moments from your departure gate:

  • Tocumen International Airport has a strong on-time record, so you're unlikely to face delays. Departures from PTY arrive at their destination as scheduled 86.03% of the time.

Panama Pacifico Airport (BLB)

  • Depending on traffic conditions, you can drive to BLB from Panama City's center in around 20 minutes. The airport is roughly 7 miles away.

  • Start your vacation sooner with an extra night away from home. Before catching your flight from Panama City to Chicago, take it easy in one of these hotels near Panama Pacifico Airport:

  • Panama Pacifico Airport is known for its commitment to punctuality. 87% of flights departing here land precisely when expected.

Arriving in Chicago

O'Hare International Airport (ORD)

  • The distance from O'Hare International Airport (ORD) to central Chicago is roughly 16 miles. It'll take you about 35 minutes to reach the center driving.

  • It typically takes 55 minutes to get there when traveling by public transport.

  • Consider booking a hotel close to ORD if you're coming in on a late flight from Panama City to Chicago. Settle into one of these options and skip the long transfer:

  • Begin your adventure by picking up an O'Hare International Airport rental car. Grab a set of wheels from Routes Car Rentals, Dollar or Budget to explore Chicago and beyond.

  • Booking your ride from O'Hare International Airport about four weeks in advance can help you get the best possible rate.

  • The street address for ORD is 10000 West O'Hare.

Chicago Midway International Airport (MDW)

  • Chicago Midway International Airport (MDW) is about 9 miles from the center of Chicago. Once you've disembarked your flight from Panama City to Chicago, it takes approximately 20 minutes to get to the heart of the city in a cab or ride-share.

  • You can expect the journey to take roughly 45 minutes on public transport.

  • After your flight from Panama City to Chicago, settle in at a hotel close to MDW. These are some comfortable options that'll help you get into relaxation mode:

  • Dollar, Hertz and Budget make collecting a Chicago Midway International Airport rental car easy and quick. These providers are located around or in the terminal and will get you on your way in no time.

  • Get what you want, not just what's left over. Booking your ride from MDW four weeks ahead of time often means better deals and a greater range of vehicles.

  • The address for Chicago Midway International Airport is 5700 South Cicero.

Chicago Rockford International Airport (RFD)

  • Hop off your flight from Panama City to Chicago and go straight to your hotel or jump right into exploring. Central Chicago is around 80 miles from Chicago Rockford International Airport (RFD) and typically takes 1 hour 25 minutes to reach by car.

  • Public transport will get you there in around 4 hours 15 minutes.

  • Take the guesswork out of the next part of your trip with a Chicago Rockford International Airport rental car. Budget, Alamo and National make getting on the road smooth sailing.

  • Rental providers sometimes offer deals for early bookings, so reserve your ride from RFD ahead of your flight from Panama City to Chicago. Plan ahead and your wallet will thank you.

  • Chicago Rockford International Airport's official address is 2 Airport Cir.

Best time to go to Chicago

  • January is the quietest month for flights from Panama City to Chicago, while August is the most popular. Choose the best time to go to Chicago based on whether you prefer a laid-back vibe or a lively atmosphere.

  • Book a Panama City to Chicago ticket departing in July if you want to experience the city during its warmest month. Expect temperatures in Chicago to range from 59ºF to 84ºF.

  • Look for cheap flights from Panama City to Chicago in January if you'd rather travel when it's cooler. Temperatures are at their lowest then, ranging between 10ºF and 37ºF on average.

More about Chicago

Explore more of United States

  • Chicago will leave a lasting impression, but there are so many other corners of United States just waiting to be discovered. About 280 miles south-east of Chicago, a visit to Columbus will keep your itinerary busy. Start with popular sights like Franklin Park Conservatory and Botanical Gardens, Ohio Statehouse and German Village.

  • Around 160 miles south-east of Chicago, Indianapolis is another essential stop in United States. Experience major highlights starting with The Children's Museum of Indianapolis, Indianapolis Museum of Art and Indianapolis Zoo.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.