$20 Flights from Palermo (PMO) to Brussels (BRUS)

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Flight deals from Palermo to Brussels

Looking for a cheap last-minute deal or the best round-trip flight from Palermo Airport to Brussels? If you want to travel next month, round-trip fares start from $41. Find the lowest prices on one-way and round-trip tickets right here.

Find the cheapest month to fly from Palermo to Brussels from $20 one-way

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Palermo to Brussels flights are currently cheapest in June.

Direct flights from Palermo to Brussels

Palermo to Brussels: Flight information

The things to know before you go.
Cheapest flight found$20
Cheapest month to flyJune
Average flight time2 hrs, 44 mins
Most popular airlineRyanair
Average flights per week15

Finding cheap flights from Palermo to Brussels: Frequently asked questions

There are 5 airports in Brussels: Brussels International, Antwerp Deurne, Brussels S. Charleroi, Liege, and Kortrijk.
The best price we found for a round-trip flight from Palermo to Brussels is $41. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours and 44 minutes is the average flight time from Palermo to Brussels.
Ryanair, Malta Air and Tuifly.be fly direct from Palermo to Brussels.
There are 45 flights per week flying from Palermo to Brussels, as of April 2026.
The cheapest month to fly from Palermo to Brussels is usually May.
If you're flying from Palermo Airport, the cheapest airport near Brussels is Brussels S. Charleroi – which is 27.4 miles away from the center of Brussels. We've found flights to this airport from $41.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Palermo Airport to Brussels on Wednesday, May 20, 2026.
Yes – the average flight time is 2 hours and 44 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Brussels but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Brussels is around 40 days in advance, so don’t leave your flight to the last minute.
In April, the average temperature is usually around 48°F. July is typically the warmest month in Brussels, when it usually averages around 72°F. You can expect the least rain in April. The coldest month is January, with temperatures averaging 31°F. The rainiest month is December.
Currently, Ryanair offers the cheapest flight tickets to Brussels.

Flying from Palermo Falcone Borsellino Airport (PMO) to Brussels: what you need to know

  • Palermo (the location of Palermo Falcone Borsellino Airport) and Brussels share the same timezone — UTC+1.

  • The most popular route is from Palermo Falcone Borsellino Airport (PMO) to Brussels South Charleroi Airport (CRL). There are six weekly services between these two airports. Ryanair offers a 06:10 departure between PMO and CRL.

  • To avoid rushing for your PMO to Brussels flight, leave plenty of time to navigate the airport and find your gate. Turning up two hours before international departures and one hour before domestic flights is the general travel rule.

  • Flying during a peak time such as July? School holidays and other high seasons can lead to longer lines at check-in and security. Play things extra safe and get there up to four hours before international flights and two hours before a domestic departure.

  • Direct Palermo Falcone Borsellino Airport to Brussels tickets are available for booking. Brussels South Charleroi Airport (CRL) is where you'll arrive.

  • Ryanair is a well-known carrier that operates direct flights from Palermo Falcone Borsellino Airport to Brussels.

  • Consider adding a stopover to potentially land a cheaper plane ticket from PMO to Brussels. Just deselect 'Direct flights only' during your search. Take a detour (and maybe pocket some savings) by stopping at one of these connection hubs:

    • Zurich Airport (ZRH)

    • Geneva Airport (GVA)

    • Milano Linate Airport (LIN)

  • Located around 15 miles from central Palermo, PMO can be reached in about 40 minutes by car. The journey on public transport takes roughly 50 minutes.

  • Planning to catch an early flight from Palermo Falcone Borsellino Airport to Brussels? Avoid the stress of rushing to the terminal (and get some extra shut-eye) by choosing one of these stays near PMO:

  • 78% of flights departing from Palermo Falcone Borsellino Airport land at their destination on schedule.

How to find the cheapest flights from Palermo Falcone Borsellino Airport (PMO) to Brussels

  • The lowest price we've seen for a one-way Palermo Falcone Borsellino Airport to Brussels flight is $20. The cheapest price for a return flight is $41. Bear in mind fares may change due to demand at the time of booking.

  • To pick up cheap flights from PMO to Brussels, reserve your trip 11 months ahead of your departure date.

  • April is the best month for picking up an awesome deal on Palermo Falcone Borsellino Airport to Brussels tickets. If you'd like to travel at a different time of year, the 'Whole month' tool will give you the lowest prices for each month.

  • There's no need to check back in every day to find out if fares have dropped when you create a Price Alert. We'll update you when there's an even bigger deal on cheap flights from PMO to Brussels.

  • Select your preferred arrival and departure times, number of stops and airlines with our filters. Then, sort the results for your flight from Palermo Falcone Borsellino Airport to Brussels by 'Cheapest,' 'Best' or 'Fastest.'

Airports in Brussels

Brussels Airport (BRU)

  • Brussels Airport (BRU) is around 8 miles from central Brussels. If you're grabbing a cab or a ride-share, the drive will take roughly 25 minutes.

  • It typically takes 20 minutes to get there using public transport.

  • The last thing you want is a lengthy journey to your hotel if you're landing late on a flight from Palermo Falcone Borsellino Airport to Brussels. Reserve one of these accommodation options near BRU instead:

  • Reserving your vehicle from Brussels Airport about three weeks before your flight from PMO to Brussels can help you lock in the best possible rate.

Brussels South Charleroi Airport (CRL)

  • Once your flight from Palermo Falcone Borsellino Airport to Brussels has hit the runway, you can get to the city center in about 55 minutes by car. Central Brussels is roughly 35 miles from Brussels South Charleroi Airport (CRL).

  • If you're catching public transport, it'll take around 1 hour 15 minutes.

  • There are some great places to park your luggage (and yourself) near CRL. Unwind and get cozy after your PMO to Brussels flight at one of these perfectly located options:

  • Snap up the best price by booking your ride from CRL two weeks in advance. You can also expect to have a wider range of vehicles.

Best time to go to Brussels

  • It's time to figure out your travel dates for your flight from Palermo Falcone Borsellino Airport to Brussels. September is the busiest month to travel to Brussels. If you prefer a quieter vibe, go in December.

  • Lock in a Palermo Falcone Borsellino Airport to Brussels plane ticket with a departure in August to experience the city during its warmest month. Expect temperatures to range from 54ºF to 81ºF.

  • If you'd rather travel in cooler conditions, search for a cheap ticket from PMO to Brussels in January when temperatures average between 28ºF and 46ºF.

More about Brussels

Explore more of Belgium

  • You've done Brussels, now it's time to explore other parts of Belgium. Travel about 70 miles west to Ostend to tick off its popular sights. From Church of Saint Peter and Saint Paul to The Crystal Ship and Mu.ZEE, there's plenty to keep you busy.

  • If you're interested in discovering another great destination in Belgium, head for Verviers, roughly 70 miles east of Brussels. Hôtel communal ou Ancienne Halle - Monument classé, Musée d'Archéologie et du Folklore and Musée des Beaux Arts et de la Ceramique are key highlights.

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.